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EP.Arimidex (anastrozole) tablets for oral administration contain 1 mg of anastrozole, a non-steroidal aromatase inhibitor.
It is chemically described as 1,3-Benzenediacetonitrile, a, a, a’, a’-tetramethyl-5- (1H-1,2,4-triazol-1-ylmethyl) Anastrozole is an
off-white powder with a molecular weight of 293.4. Anastrozole has moderate aqueous solubility (0.5 mg/mL at 25°C); solubility
is independent of pH in the physiological range. Anastrozole is freely soluble in methanol, acetone, ethanol, and tetrahydrofuran,
and very soluble in acetonitrile. Each tablet contains as inactive ingredients: lactose, magnesium stearate, hydroxypropylmethylcellulose,
polyethylene glycol, povidone, sodium starch glycolate, and titanium dioxide.